Annabeth Gish

as Monica Hawkins

as Dr. Joyce Hendricks

as Eliza

as Kathy

as Denise Westfield

as Billie Riggs

as Deirdre Mayfair

as Doctor Jennice

as Self - Host

as Dr. Sarah Gunning

as Jennifer Farber Dulos

as Detective Lincoln

as Bonnie Breaker

as Self

as Grace

as Virginia Carlson

as Mrs. Dudley

as Maddie Stewart

as Charity

as Joy Palmer

as Julie

as Alice

as Mrs. Turner

as Lucy

as Natalie

as Geraldine Lithwick

as Diane Gould

as Self

as Charlotte Millwright

as Annette Davis

as Maddie Stewart

as Michelle

as Rachel Garano

as Lillian Forrester

as Jo Noonan

as Anita

as Gwen Heigh

as Chief Julie Carmen

as Beth

as Lynne

as Alice Sands

as Dr. Anne Sullivan

as Det. Delma Sykes

as Melody York

as Lita

as Stephanie Wyatt

as Ilene Clark

as Meg Maxwell

as Sally Linden

as Althea Jarry

as Lydia

as Beth

as Eileen Caffee

as Julia

as Mary Jackson

as Rebecca Hodges

as Narrator

as Cynthia Ernst

as Greta Siegel

as Denise Di Fiori

as Wendy Decker

as Nicole

as Mary Follet

as Dr. Donni McGuinness

as Amie

as Marissa

as Laura Gabriel

as Angie Green

as Elizabeth Bartlet-Westin

as Carolyn Rivers

as Robbie

as Claire Hutton

as Hope Goodell

as Trish

as Karen Holmes

as Sparky

as Euphemia Ashby (adult)

as Maria Philips

as Jean Treadway Holly

as Michelle

as Tracy Stover

as Julie Nixon Eisenhower

as Lenore Laderman

as Paulie

as Anne Butler (née Hampton)

as Amy Peletier

as Urilla Sutherland

as Monica Reyes

as Hazel Hampton

as Sylvia Raffray

as Lydia

as Tammy

as Lyn McKenna

as Caroline "Pudge" Carmichael

as Kat

as Ryan Campbell

as Jessie

as Rosalie "Rose" Chismore

as Lydia

as Diane